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Peer review Peer review information Nature Reviews Drug Discovery thanks Michael Nauck, Stefan Trapp and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Wegovy commonly causes nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation

Helps regulate blood glucose levels, which can reduce energy dips that trigger snacking

Clinical Considerations Healthcare providers often take a cautious approach when prescribing semaglutide, especially at higher doses, for patients with a history of GERD

Reduce intake of gas-producing foods like beans, cabbage, onions, and Brussels sprouts if they cause problems, and reintroduce them gradually