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Rubio, G

El estreimiento es un efecto adverso comn en pacientes que toman agonistas GLP-1 como semaglutida (Ozempic, Wegovy) o tirzepatida (Mounjaro, Zepbound), afectando entre el 3% y el 24% de los usuarios segn el medicamento especfico

doi: 10.1038/nrendo.2012.140 19 MarsoSPDanielsGHBrown-FrandsenKKristensenPMannJFNauckMAet al

Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications primarily used to manage type 2 diabetes mellitus and, more recently, obesity

The expression levels of ABCA1 and ATP-binding cassette G1 (ABCG1) can also be increased by GLP-1, which inhibits the transformation process of macrophages into foam cells and reduces the level of intracellular cholesterol