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Its relatively simple structure and stable copper-binding configuration make it a useful model compound for investigating metal-regulated signaling pathways and peptide-mediated trace element transport in preclinical systems

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Since mitochondria are the primary source of ROS, we observed through MitoSOX Red staining the mitochondrial ROS of PANC-1 cells, which were the cells with the most marked increase in ROS level (Fig

GBS primarily involves flexia and symmetrical limb weakness [132]

Indeed, while in many cases it would be desirable or crucial to specifically target a particular GST isozyme or polymorphic form, this is hardly achievable with the molecules synthesized and investigated so far