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Furthermore, the SUMMIT HFpEF trial with tirzepatide, another GLP-1RA, also demonstrated benefits in obesity-related HFpEF, including reductions in heart failure events and improvements in functional capacity, alongside weight loss 37

Magnetic resonance spectroscopy Magnetic resonance spectroscopy (MRS) complements these studies: it provides lower sensitivity and, in many cases, less molecular specificity than neurochemical analyses of CSF, but it permits investigation of levels of glutamate and related molecules in specific brain regions, which CSF analysis cannot do

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Timing plays an important role in achieving lasting results

Both are growth hormone secretagogues, but they work through different receptors