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Mesenchymal stem cell transplantation exerts a beneficial role also in the EAE mice, the animal MS model, promoting a functional recovery ( 2+ levels by the modulation of calbindin expression, which is associated with calcium homeostasis and plays a role in the protection of dopaminergic neurons in the pathogenesis of PD (Liu et al., 2014)

Unlike simply increasing the dose of a single agonist, combining two complementary signalling pathways allows research to model a stronger overall effect with a controllable adverse-event profile

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The biggest culprits are coffee, soda, tomatoes, citrus and spicy foods