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The Role of Lifestyle Modification with Second-Generation Anti-obesity Medications: Comparisons, Questions, and Clinical Opportunities

Key takeaways GLP-1 medications are one of today's most popular weight-loss options, but getting the most out of them may start with asking the right questions

How often will I need follow-up visits, lab work, or other tests

Clinically, these phases can look remarkably similar

found that GLP-1 receptor agonist use, compared with initiation of sodium-glucose cotransporter 2 (SGLT2) inhibitors, was associated with a lower risk of composite MALOs (aHR: 0.84, 95%CI: 0.74-0.94), including specifically lower occurrence of liver decompensation (aHR: 0.83) and all-cause mortality (aHR: 0.84) [56]