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Studies using various animal models of dementia to test the influence of Nle 1 -AngIV have demonstrated reversal of deficits initiated by: (1) treatment with scopolamine (73)

This is generally tolerated without treatment and limited to day after injecting

Research demonstrates that when formulated as solid lipid nanoparticles, curcumin shows enhanced neuroprotective activity against epilepsy by activating both Bcl-2 family proteins and p38 MAPK signaling pathways (Huang et al., 2020)

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