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Pumpkin polysaccharide modifies the gut microbiota during alleviation of type 2 diabetes in rats

The arrival of the Wegovy pill (semaglutide), the first oral GLP-1 drug approved to treat obesity, means freedom of choice: Adults who are looking to lose weight and have at least one weight-related medical condition can now take Wegovy as a once-daily pill instead of a weekly injection

Since the nanoparticle delivery system can increase the absorption and bioavailability of bioactive substances, it has been widely employed for bioactive chemicals whose low absorption limits their biological activity and bioavailability 78

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Furthermore, mobilization of metals from various compartments in the body could occur due to certain stressors such as disease, trauma, starvation, pregnancy, time of life (e.g., menopause), and extreme emotional impacts