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Some medicines may reduce the effectiveness of the oral contraceptive pill, particularly if they cause vomiting or diarrhoea, so an alternative or additional method of contraception may be needed

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Side Effects & Safety Injection site reactions -- redness, swelling, stinging (common with large-volume SC injections) Flu-like symptoms -- mild fever, fatigue, malaise 24-72 hours post-injection (possibly from immune clearance of apoptotic cells) GI discomfort -- nausea, mild digestive upset Temporary fatigue -- 1-3 days post-injection Off-target cell death (theoretical) -- no compound is perfectly selective

doi:10.3390/ijms241512152 Peters B, Hadimeri H, Wahlberg R, Afghahi H