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and safety concerns around promoting apoptosis given the potential for off-target effects in stem cell populations that share some SASP markers

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It is interesting to note that other post-acute infection syndromes (PAIS) and some neuropsychiatric diseases such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), depression (especially the atypical/immunometabolic subtype (IMD) [86]) and others also have fatigue as a leading clinical symptom, which may serve as a model for investigating the mechanisms of fatigue and drawing conclusions regarding therapeutic options in long COVID

It is particularly valuable for individuals with low muscle tone, coordination disorders, or delayed motor milestones