bruise at tirzepatide injection site Rash from a GLP-1 explained by an allergist 👆, Thanks to my friend @rubin_allergy for the information in this video Botox® Bruising: Understanding and Managing

In SURMOUNT-1, 72 weeks of tirzepatide induced mean WL of 1622.5% in people without diabetes compared to 2.4% with placebo, with no sign of the weight plateauing, suggesting that there may be further WL with long-term use [46]

It also disrupts ER Ca 2+ pool homeostasis, triggering ERS, interfering with protein degradation, and leading to protein accumulation

Large oral doses of MCT may cause osmotic diarrhea, especially when taken on an empty stomach

Gaudier et al., 2004)

If the app also records key efficacy, safety/tolerability and PROs, we have everything needed to refine how we can maximise individual benefits versus individual harms