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10.1042/cs20180885 Clin

Cardiac AMPK complexes consist predominantly of alpha 2, beta 2, and gamma 2 subunits [18] and act as an important regulator of LCFA oxidation and glucose uptake in the heart [19]

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For patients and clinicians, this was a novel mechanism a drug for diabetes that caused weight loss and had low hypo risk was almost unheard of at the time

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