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It is known that free radicals are responsible for diseases such as atherosclerosis, diabetes, epilepsy, inflammatory diseases and cancer

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The peptide was first identified in the 1990s in the saliva of the Gila monster, a type of lizard

(B) Semaglutide, as a GLP-1 analog, can directly act on fat cells, increase the expression of thermogenic genes for browning phenotype maintenance, improve the expression of uncoupling protein 1 (UCP1), mitochondrial biosynthesis, and thermogenic marker, or promote fatty browning through nitric oxide synthase (NOS), neuropeptides (NPs), sirtuin 1 (STRT1), signal transducer and activator of transcription 3 (STAT3), and bone morphogenetic protein 4 (BMP4) signaling