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doi:10.1016/j.jacl.2011.03.002

Mechanistically, elevated BCAA slevels exacerbate oxidative stress through two distinct pathways: (i) increased circulating BCAAs enhance ROS production in peripheral blood mononuclear cells (PBMCs) via mTOR signaling hyperactivation, resulting in PBMC overactivation (Zhenyukh et al., 2017)

A narrative review conducted by Trujillo investigated the relative risks for associated adverse effects (such as GI symptoms, hypoglycemia, injection-site reactions, pancreatitis, neoplasms, gallbladder disease, and diabetic retinopathy) among three GLP-1 RAs when injected once weekly

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