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Symptoms are most likely to appear during dose increases or near the target dose and often improve as the body adjusts over time

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With enormous diversity in chemical and physiological properties, these molecules serve a wide variety of purposes, including as important components of the bacterial cell envelope 7,30,34 , providing protection against desiccation and toxic substances 87,88,89 , mediating attachment to surfaces 87,90 , biofilm formation 91,92 , host interaction 93,94 , and bacterial motility 58,60

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