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The protocol (Supplementary Appendix A) was developed in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines [6] and has been published on PROSPERO (ID: CRD420251051447)

The gut microbiome composition will never look that way again once human milk feeding stops or is supplemented with other foods

doi: 10.3390/ijms24043950 2 FarageMAMillerKWBerardescaEMaibachHI

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Although 35 month-old mutants and controls habituated similarly, 810 month-old mutants showed an altered response to the testing environment and were unable to habituate (Fig