The clinical trial headlines are impressive, 14.9% average body weight reduction in the STEP 1 trial, but averages don't tell you what to expect in any given week or month
The appropriate duration of contraception after stopping will depend on the specific agent and trial protocol
Editorials and reviews in major journals have stressed that while triple agonists look very promising, their safety over many years will need careful surveillance, especially with respect to cardiovascular health, pancreatic function, and potential rare adverse events that may not appear in mid-sized trials
Throughout the study, participants were advised to eat a healthy diet and exercise with the goal of weight loss
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