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Ubidecarenone enhances succinate-dependent and glycerol-3-phosphate-dependent ROS generation, mitochondrial membrane depolarization, and regulated cell death Impairments to the mitochondrial ETC, in particular the loss of efficiency in electron transfer from Complex III or mGPDH to oxygen (as reported above), can result in electron leakage and ROS generation 10

Zhang Z, Zhai H, Geng J, Yu R, Ren H, Fan H, et al

In brief, the peak area of the metabolite was normalized to the peak area of an isotopically labelled internal standard with similar elution time, both in samples from culture medium and external standard library dilutions

[DOI] [PMC free article] [PubMed] [Google Scholar] 164.Jindal A., Mainuddin, Kumar A., Ratnesh R.K., Singh J

Though effective, they must be done under expert supervision to avoid burns or sensitivity