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Since the reaction of converting thiol to disulfide occurs under biological conditions in the presence of oxidizing agents such as flavins, cytochromes, and dehydroascorbic acid (Peer et al

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Patients with SLE exhibit gut microbial dysbiosis characterized by reduced microbial diversity and elevated serum LPS levels [154]

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The solubility of urate declines progressively at cooler temperatures, such as those in the distal peripheral joints (e.g., first metatarsophalangeal [MTP] joint) where urate crystals typically first deposit in gout

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