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Hierarchical clustering and heatmap analysis illustrated expression patterns across the groups

GIPR expression in the brain, particularly in the hypothalamus and ventral tegmental area, appears to modulate reward-driven feeding behaviour through a distinct mechanism [3]

A separate peer-reviewed 2025 study published in Diabetes, Obesity and Metabolism, drawing on data from more than 440,000 adults attending Dubai Academic Health Corporation, found 63% overweight or obese, with 28% classified as obese by BMI criteria