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The principles are identical

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Exenatide may provide cardioprotective effects through several pathways associated with metabolism, contractility, reduction of apoptotic cell death, and anti-inflammatory effect

However, losing weight often comes with losing some muscle mass, which is not ideal

Unlike older weight loss medications, Retatrutide activates three different receptors (GLP-1, GIP, and glucagon), creating a synergistic effect that amplifies fat burning and appetite control beyond what single or dual receptor agonists achieve