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This connection may be mediated by the gut microbiota and polyphenol-derived microbial metabolites, which also exert biologically relevant effects

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The utilization of RNA-Spiegelmers (stable oligonucleotides with specific target binding properties) is another method for blocking the orexigenic effects of ghrelin

Elevated LOXL2 expression in estrogen receptor-negative breast tumors is strongly associated with unfavorable outcomes, including poor prognosis, decreased overall survival, and reduced metastasis-free survival, suggesting that LOXL2 could serve as a valuable prognostic marker for metastasis in breast cancer cases