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RNA sequencing Total RNA was isolated from the Achilles tendon using the ISOGEN reagent (Nippon Gene, Tokyo, Japan)

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2.3 Statistical methods The study compared whether there were significant differences in proportion of gender, age, and weight across AEs between the serious and non-serious outcomes among the different medications (including albiglutide, exenatide, dulaglutide, liraglutide, semaglutide, and tirzepatide)