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Patients with LN were excluded from such studies due to the potential necessity of acute immunosuppression ( Recently, we have published a pilot study in patients with LN on stable immunosuppressive treatment and non-immunosuppressive treatment with RAASi to whom a 10-mg dose of empagliflozin was added, obtaining a 50% reduction in residual proteinuria with minimal changes in eFGR and with few side effects ( GLP-1RA Glucagon-like peptide one receptor agonists (GLP-1RA) is a class B G protein-coupled receptor expressed in the pancreas and central nervous system but is also present in other organs such as the gut, kidneys, lungs, liver, heart, muscle, and peripheral nerves

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Research has also examined its potential role in appetite regulation and weight management