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The concentration of APs was markedly enhanced in GO (+ 244%), GO + amlodipine (+ 136%), GO + aminoguanidine (+ 20%), and GO + NAC (+ 105%) versus BSA (Fig

10.24875/RIC.20000208 59 Vidal-AlaballJ.ButlerC

Ash weight was increased by all treatments, but the mineral concentration was unchanged

For reference, the branded Mounjaro 2.5 mg once-weekly equivalent on a 6 mg/mL vial would be approximately 42 units (0.42 mL), but that schedule is not the RxPepsDirect protocol

Research endpoints include epithelial-barrier integrity, cytoprotective signaling, inflammatory-response markers, peptide biodistribution, and comparisons with parenteral delivery models