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Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases

In a phase 1 double-blind randomized study, in which participants either received LY3298176 or a placebo, Coskun et al

Molecular Architecture Designing Balanced Activity Across Three Receptors Designing a balanced triple-receptor agonist is substantially more constrained than designing a single-receptor or dual-receptor compound

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At normal dietary L-carnitine intake, whole-body turnover time in humans is 38-119 hr