If we go back to first principles and foundational biochemistry, we definitely want to support glutathione production, via its precursor amino acids: cysteine, glycine, and glutamate, and the biochemical pathways and cofactors involved in its production (e.g., methylation cycle, B vitamins especially B2, B3, B6, B9,and B12)
Patients should be cautious about products that promise rapid weight loss, dramatic appetite suppression, or results equal to prescription injections without medical supervision
Anticancer Agents Med Chem 15:647656
Vegans or people with certain genetic problems may not be able to produce sufficient amounts of carnitine themselves or ingest them from external sources
Research published in 2025 suggests this risk is real but depends on factors like GLP-1 dose, individual metabolism, and whether you take other medications that further slow digestion