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Mutation in mitochondrial ribosomal protein S7 (MRPS7) causes congenital sensorineural deafness, progressive hepatic and renal failure and lactic acidemia

6.5 Effects on cardiovascular outcomes The effects of tirzepatide on cardio metabolic risk factors and vascular consequences have been investigated in the context of the SURPASS trials

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In the SURMOUNT-1 trial, 91% of participants on 15 mg lost at least 5% of their body weight, and 57% lost 20% or more