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[1] Patients with a history of severe gastrointestinal disease, including gastroparesis, should be monitored closely

Sensitivity Analysis: Requirement for at Least Two Prescriptions for Baseline GLP-1 RA Prescription data reflect which medications are prescribed, but such prescriptions are not always collected and then used by the individual

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Despite medical intervention, her condition rapidly deteriorated, leading to impaired kidney function, coma, and ultimately, multiple organ failure

Other contributing factors include medication interactions (certain psychiatric medications, corticosteroids, and reduced exposure to oral contraceptives during dose escalation), hormonal changes (thyroid dysfunction, menopause), inadequate sleep (less than 7 hours nightly), chronic stress with elevated cortisol, and reduced physical activity as patients become more comfortable at their current weight