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The underlying mechanisms of such HFD-induced systemic metabolic endotoxemia due to dysbiosis might involve low-grade intestinal inflammation and enhanced gut permeability [159]

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Acknowledgements This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (the Ministry of Science & ICT, MSIT) (RS-2024-00350878 and RS-2023-00242443), and by the Korean Fund for Regenerative Medicine (KFRM) funded by MSIT and the Ministry of Health and Welfare, Republic of Korea (RS-2025-02223118)