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The cumulative incidence was 8.9% for semaglutide and 1.8% for the non-GLP-1 RA group over 36 months

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it does not reduce glucose levels on its own

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(New England Journal of Medicine) That evidence base is why GLP-1s are viewed clinically as foundational metabolic therapeutics rather than just weight-loss drugs. The peptide wave: what people usually mean (and why its not one thing) When patients say Im looking into peptides, theyre usually referring to one (or more) of these buckets: Body composition / muscle-support peptides Often marketed to preserve lean mass during fat loss or improve training adaptation