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We can divide current evidence into three main categories: In Vitro Studies This refers to research thats been conducted in isolated cells and laboratory environments

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doi: 10.1097/00003246-200104000-00005

Factors that contribute to the severity of opiate withdrawal symptoms include: How much you have been using Duration of opiate abuse Underlying mental health disorders Medical History Age History of chronic pain Mixing opiate abuse with other substances Overall health It is important to remember that no matter how long you have been abusing opiates, opiate detox is uncomfortable