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It: Stimulates insulin release when glucose is high Suppresses glucagon (which normally raises blood sugar) Slows gastric emptying Signals satiety to the brain Semaglutide essentially amplifies this pathway

[DOI] [PubMed] [Google Scholar] 72.Best M.W., Wu J., Pauli S.A., Kane M.A., Pierzchalski K., Session D.R., Woods D.C., Shang W., Taylor R.N., Sidell N