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Ingold I, Aichler M, Yefremova E, Roveri A, Buday K, Doll S et al (2015) Expression of a catalytically inactive mutant form of glutathione peroxidase 4 (Gpx4) confers a dominant-negative effect in male fertility

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In contrast to the accumulation of cells in the G 1 phase occurring in the cultures of normal fibroblasts at a very high density in an LMet-supplemented medium, LMet restriction selectively arrested cancer cells in the S/G 2 -phase and eliminated clonogenic cells (equivalents of tumor-initiating cells) and rendered cancer cells sensitive to cell-cycle-specific drugs [14, 28, 31]

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