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This is the receptor that the drug is acting on. The missense variant may affect how much receptor is expressed on the cell surface, meaning individuals with more receptors could experience a stronger response to the same dose

Responsible education acknowledges that: Sun exposure still plays a role Results vary by skin type Gradual, moderate exposure is essential Sun safety should always be prioritised Clear, honest explanations improve credibility and align with regulatory expectations

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Cui, H., Feng, C., Zhang, T., Martnez-Ros, V., Martorell, P., Tortajada, M., Cheng, S., Cheng, S., & Duan, Z

Retrieved March 12, 2013