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However, for individuals seeking durable, lifelong results without reliance on continuous prescriptions, bariatric surgery may offer greater stability

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Sensitivity analyses To assess the robustness of our findings, we conducted a subgroup analysis by grouping RCTs by seven primary outcome categories (e.g., Parkinsons disease, Alzheimers disease, Lewy body dementia, multiple sclerosis, amyotrophic lateral sclerosis, frontotemporal dementia, and Huntingtons disease)

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A higher percentage of participants in the pramlintide groups achieved a weight loss of at least 10% at the 12-month mark compared to the placebo group (40% and 43% vs