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Other mechanisms explaining the effects of metformin on thyroid cell growth and viability are the downregulation of cyclin D1, the increase of the ER stress and the reduction of mRNA levels of AKT, PI3K, and FOXO1 LRP2 and p-JNK, genes that play a crucial role in cell proliferation and survival (Oyadomari and Mori, 2004

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Discovery of a bacterial peptide as a modulator of GLP-1 and metabolic disease

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Reduction in Appetite and Caloric Intake: By affecting hunger hormones and gastric emptying, GLP-1 can help reduce appetite and caloric intake, leading to weight loss