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The vicious cycle of type 2 diabetes mellitus and skeletal muscle atrophy: clinical, biochemical, and nutritional bases
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Excessive production of reactive oxygen species (ROS) activates redox-sensitive signalling pathways such as NF-B, leading to sustained release of pro-inflammatory cytokines including TNF-, IL-6, and IL-1, which impair fibroblast function, collagen synthesis, keratinocyte migration, and neovascularisation
Coffee has also been linked to increased stomach acid, which could impact how an oral GLP-1 is absorbed
It occurs in all body cells in different concentrations, mainly in the liver, brain and kidneys as well as in the red and white blood cells
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