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Park E, Chung SW

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Since glutamate is one of the brains major excitatory neurotransmitters, this pathway has drawn interest in conditions such as obsessive-compulsive disorder (OCD), depression, bipolar disorder, and substance use disorders.11 29 The evidence is still uneven

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However, at this stage its not clear if SURMOUNT-5 is designed to detect Mounjaros superiority (rather than non-inferiority)