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In some embodiments, the otic formulation or composition comprises between about 0.01% to about 30% by weight of the carbomer

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Each component has been studied for its role in age-aligned metabolic pathways

The average duration for returning to play was 21.1 3.1 days for the PRP group and 25 2.8 days for the control group (P = 0.001)

Lyophilization, or freeze-drying, is a process where the peptide solution is frozen and then placed under a vacuum, causing the ice to sublimate (turn directly into vapor) without passing through a liquid phase