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Mounting Evidence Links GLP-1 Drugs to Serious Health Issues For years, scientific studies have showed a link between the GLP-1 drugs and increased risks of serious gallbladder-related diseases and gastrointestinal issues, including: A 2016 study of over 70,000 patients found GLP-1 drugs associated with a significantly increased risk of bile duct and gallbladder disease compared to other oral antidiabetic drugs

GLP-1 receptor agonists mimic the action of glucagon-like peptide-1, a naturally occurring hormone that regulates blood sugar and appetite

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Another promising strategy is intranasal delivery, which bypasses the BBB via olfactory and trigeminal pathways [275, 276]

Learn about the safety of crushing vitamin pills, tablets, capsules or enteric-coated tablets and ingesting the powder with food, as opposed to taking a whole pill