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In these populations, there is an increased chance of malignancy, and an even greater chance of other GI pathology that can be intervened on

A new drug, compound 6, does just that

To better assess its clinical effect in patients with SCD, a pilot study, currently enrolling with invitation is studying its effect in redox and RBC function during VOC (ClinicalTrials.gov Identifier: NCT01800526)

**BPC-157, a synthetic gastric pentadecapeptide studied primarily in animal models for tissue repair, gut healing, and anti-inflammatory effects, remains unapproved by the FDA as a finished drug with only limited small-scale human data available.** It was placed in Category 2 in 2023 due to concerns over immunogenicity, peptide impurities, and insufficient safety information for compounding under Section 503A

Clinical trials show 515% body weight reduction is typical within 1216 weeks, which for most adults equals 1020 pounds