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In the CIA mouse model, resistance of TNF-induced synovial fibroblasts to ferroptosis can be eliminated by adding a low dose of IKE (20 mg/kg, twice a week) and a low dose of TNF inhibitor

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Statistical analysis was performed using GraphPad Prism software (v

Clin Microbiol Rev 15(1):111124 Flaxman SR et al (2017) Global causes of blindness and distance vision impairment 19902020: a systematic review and meta-analysis