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However, the timeline for recovery varies considerably between individuals

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While bloating alone rarely necessitates medication discontinuation, persistent severe symptoms warrant thorough evaluation to exclude serious pathology and optimize the treatment regimen

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Serious adverse events are less common but documented: pancreatitis, gallbladder disease, hypoglycemia (particularly in patients on concomitant diabetes medications), and a boxed warning regarding medullary thyroid carcinoma risk in rodent studies - a finding whose clinical significance in humans at therapeutic doses remains under study