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The 28-day planning problem Here is a practical issue the charts alone do not solve

Available: Guo, F., Bakal, K., Minokoshi, Y., & Hollenberg, A

When to pause or reverse the taper Red flags that should pause your taper include weight gain exceeding 3% of your lowest weight, significant increase in hunger that interferes with daily functioning, worsening metabolic markers such as rising blood sugar, blood pressure, or lipid levels, return of binge eating patterns or loss-of-control eating episodes, and significant emotional distress related to appetite changes

Elevated acylcarnitines are also associated with insulin resistance, a known risk factor for cardiovascular diseases

It establishes an elevated risk of psychiatric consequences associated with these treatments, particularly in the domains of depression, anxiety, and suicidal outcomes