MOTS-c: the mitochondrial peptide for disc cell survival MOTS-c is a 16-amino-acid peptide encoded by the mitochondrial genome that has recently emerged as a promising candidate for intervertebral disc degeneration
Separate vials allow independent dose control, which matters for TB-500-heavy injury protocols, but they require more injections per session and three reconstitutions
People with high insulin resistance (ie, people with obesity), young age at dysglycaemia, abnormal 1 h glucose concentrations (86 mmol/L) despite normal 2 hr glucose concentrations on 75 g oral glucose tolerance test, and low C-peptide are at higher risk for progressing to stage 3 (fast progressor, stage 2b) than those diagnosed with dysglycaemia after age 65 years (slow progressor, stage 2a)
doi: 10.1021/acs.chemrestox.7b00311
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