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435 HSPs and inflammasome regulation in autoimmune diseases Inflammasomes are multiprotein complexes that play a central role in innate immunity by regulating the production of pro-inflammatory cytokines, such as interleukin-1 (IL-1) and IL-18

The cells basically get tired of hearing the same signal and start to pull the receptors from their surface, making them less sensitive

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Collagen serves as the structural glue of the body, making up most of your skin to maintain firmness and prevent wrinkles