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Other GLP-1 receptor agonists that are FDA-approved to treat type 2 diabetes and may lead to weight loss include: Dulaglutide (Trulicity) Exenatide (Bydureon) Lixisenatide (Adlyxin) Other forms of semaglutide (Ozempic and Rybelsus) Many diabetes medications and insulin reduce blood sugars but also contribute to weight gain

Regulatory decisions are anticipated in 2026

Caroline Apovian, the co-director of the Center for Weight Management and Wellness at Brigham and Women's Hospital, agrees: "The studies show over and over and over again," Apovian says, that if you stop taking the medications, "you will regain the weight back." Noom isn't the only startup to market GLP-1s as temporary treatments that offer long-term effects

While alcohol is currently the primary focus, interest is expanding to other substance use disorders, including nicotine dependence and opioid use

The only GLP-1 formula with probiotics, an essential factor for GLP-1 long-term maintenance, and fenugreek which helps slow down carbohydrate digestion and absorption, enhancing GLP-1 secretion