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Furthermore, diminished levels of growth factors such as IGF-1 and GDF-9 within the follicular microenvironment may further contribute to poor oocyte competence and suboptimal embryo development ( These disruptions highlight the multifactorial impact of the altered ovarian niche in endometriosis, offering a rationale for targeted antioxidant, anti-inflammatory, or ferroptosis-modulating therapies aimed at restoring follicular health and reproductive potential

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The fluidic and elastic properties of the nanoemulsions enabled them to effectively pass through the interstitial spaces of the stratum corneum, while the CPP decoration further enhanced skin penetration and cellular uptake of Cur-CNEs

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