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doi: 10.1016/j.bbr.2012.09.021 146 AlhadeffALRupprechtLEHayesMR

Tirzepatide and GIP treatment lead to significantly lower interleukin-1 beta (IL1B) levels and Tirzepatide further lowered interleukin-6 (IL-6) and monocyte-chemoattractant protein-1 (MCP-1) levels, highlighting distinct tissue-specific regulatory roles in pancreatic adipose tissue metabolism and inflammation [32]